Triethylamine → HCID 19107030, compound

HRID 1460592Notes

Reaction equation

HRID 1460592 reaction equation
[CH:1]1[C:10]2[C:9]3(C(O)=O)[CH2:11][CH2:12][CH2:13][CH2:14][CH:8]3[CH2:7][O:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.C1(P(N=[N+]=[N-])(C2C=CC=CC=2)=[O:25])C=CC=CC=1.C([N:37]([CH2:40]C)CC)C>C1(C)C=CC=CC=1>[N:37]([C:9]12[CH2:11][CH2:12][CH2:13][CH2:14][CH:8]1[CH2:7][O:6][C:5]1[CH:4]=[CH:3][CH:2]=[CH:1][C:10]2=1)=[C:40]=[O:25]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 199401P,P-Diphenylphosphinic azideHCID 19107117HCID 19107117, compound

Product 1

HCID 19107030HCID 19107030, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of the compound from Example 70 (1.0 g, 4.30 mmol) and diphenylphosphorylazide (1.3 g, 4.7 mmol) in 1.1 ml triethylamine and toluene was refluxed for 15 hours. Workup and silica gel chromatography gave the title compound (0.71 g) as a clear oil.

Sources & evidence

ORD record
ord-247d5676c1af41d384ab668aa703a792
Source dataset
uspto-grants-1991_12
Patent number
US05071853

Reaction notes

Loading…