HCID 131717094, compound → HCID 57178061, compound

HRID 1460609Notes

Reaction equation

HRID 1460609 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH:9]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][C:10]1=[N:16][C:17](=[O:21])[O:18][CH2:19][CH3:20].C([Li])(C)(C)C>O1CCCC1>[CH:4]1[C:3]2[CH2:8][CH:9]3[C:10]([NH:16][C:17](=[O:21])[O:18][CH2:19][CH3:20])([C:2]=2[CH:7]=[CH:6][CH:5]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]3

Participants

4

Reactant 2

HCID 131717094HCID 131717094, compoundHCID 178418306HCID 178418306, compound

Product 1

HCID 57178061HCID 57178061, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution of the N-ethoxycarbonylimine (3.38 g, 0.1 mole) from Example 167 nin dry tetrahydrofuran (100 ml) cooled to -78° C. is treated with t-butyllithium in a similar manner to that described in Example 83 to afford after workup the title compound.

Workup

  1. customto afford

Sources & evidence

ORD record
ord-83cb918af91a450198bcdf198bdbd216
Source dataset
uspto-grants-1991_12
Patent number
US05071853

Reaction notes

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