反应详情

A solution of 150 mg of the title compound of example 5 in 5 ml of dichloromethan and 5 ml of dioxan is mixed with 77 mg of N-chloro-succinimide. After 50 minutes at room temperature the solution is poured on water and the organic components are extracted with dichloromethane/ethanol. Recristallisation of the raw product obtained after concentration yields white crystalls of the title compound having a m.p. of 288°-89° C.

1. additionAfter 50 minutes at room temperature the solution is poured on water
2. extractionthe organic components are extracted with dichloromethane/ethanol
3. customRecristallisation of the raw product obtained
4. concentrationafter concentration