Hydrochloric Acid → 2-amino-6-chloro-9-(trans-4-hydroxycyclohexyl)-7H-purin-8(9H)-one

HRID 146068Notes

Reaction equation

HRID 146068 reaction equation
[C:1]([O:2][CH:3]1[CH2:4][CH2:5][CH:6]([n:9]2[c:10]3[n:11][c:12]([NH2:20])[n:13][c:14]([Cl:19])[c:15]3[nH:16][c:17]2=[O:18])[CH2:7][CH2:8]1)(=[O:21])[O:22][CH3:23].[ClH:24].[K+:26].[OH-:25]>>[OH:2][CH:3]1[CH2:4][CH2:5][CH:6]([n:9]2[c:10]3[n:11][c:12]([NH2:20])[n:13][c:14]([Cl:19])[c:15]3[nH:16][c:17]2=[O:18])[CH2:7][CH2:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 961HydroxideHCID 57612721Trans-4-(2-amino-6-chloro-8-oxo-7,8-dihydropurin-9-yl)cyclohexyl methyl carbonate

Product 1

HCID 576126532-amino-6-chloro-9-(trans-4-hydroxycyclohexyl)-7H-purin-8(9H)-one

Sources & evidence

ORD record
ord-c0337dd38424422e8a1ac0ca47258c0c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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