Water → HCID 19100973, compound

HRID 1460797Notes

Reaction equation

HRID 1460797 reaction equation
[F:1][CH2:2][C:3](=[CH2:14])[CH2:4][N:5]([CH2:11][CH:12]=O)[C:6](=[O:10])[O:7][CH2:8][CH3:9].O.[NH:16]([CH2:18]C(O)=O)[CH3:17]>C1(C)C=CC=CC=1>[F:1][CH2:2][C:3]12[CH2:4][N:5]([C:6]([O:7][CH2:8][CH3:9])=[O:10])[CH2:11][CH:12]1[N:16]([CH3:18])[CH2:17][CH2:14]2

Participants

5

Reactant 3

HCID 962WaterHCID 1088SarcosineHCID 19738514HCID 19738514, compound

Product 1

HCID 19100973HCID 19100973, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

9.1 g (43 mmol) of ethyl N-(2-fluoromethylallyl) -N-(2-oxoethyl)-carbamate are heated under reflux overnight in a water separator with 3.9 g (43 mmol) of powdered sarcosine in 170 ml of toluene. The mixture is concentrated and the residue is distilled.

Workup

  1. concentrationThe mixture is concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-46ed80427eb24ea4bca35732ffcf7b0c
Source dataset
uspto-grants-1991_12
Patent number
US05071999

Reaction notes

Loading…