Water → HCID 19738537, compound

HRID 1460804Notes

Reaction equation

HRID 1460804 reaction equation
Cl[CH:2]([CH3:5])[CH:3]=[CH2:4].[CH3:6][O:7][CH:8]([O:16][CH3:17])[CH2:9][NH:10][C:11](=[O:15])[O:12][CH2:13][CH3:14].[OH-].[K+].O>CN(C)C=O>[CH2:4]=[CH:3][CH:2]([N:10]([CH2:9][CH:8]([O:7][CH3:6])[O:16][CH3:17])[C:11](=[O:15])[O:12][CH2:13][CH3:14])[CH3:5]

Participants

6

Reactant 4

HCID 962WaterHCID 112423-Chloro-1-buteneHCID 14797Potassium HydroxideHCID 10921057Ethyl 2,2-dimethoxyethylcarbamate

Product 1

HCID 19738537HCID 19738537, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

22 g (0.24 mol) of 3-chloro-1-butene are added to 35.5 g (0.2 mol) of ethyl N-(2,2-dimethoxyethyl)-carbamate and 26 g of powdered potassium hydroxide in 400 ml of dimethylformamide and the mixture is warmed overnight. to 40° C. The salts are dissolved with water and the mixture is extracted several times with methylene chloride. The organic extracts are dried over potassium carbonate and concentrated, and the residue is distilled.

Workup

  1. temperaturethe mixture is warmed overnight
  2. customto 40° C
  3. extractionthe mixture is extracted several times with methylene chloride
  4. dry with materialThe organic extracts are dried over potassium carbonate
  5. concentrationconcentrated
  6. distillationthe residue is distilled

Sources & evidence

ORD record
ord-c2ea1c34dceb4cd2946b77c1b7c53707
Source dataset
uspto-grants-1991_12
Patent number
US05071999

Reaction notes

Loading…