Ethanol → HCID 15124394, compound

Participants

Reaction Steps

100 ml stainless steel autoclave was charged with 2.2 g (20 mmol) of resorcin, 5.28 g (40 mmol) of acetone diethyl acetal, 9.2 g (200 mmol) of ethanol, 0.2 g (2 mmol) of conc. sulfuric acid and 40 ml of toluene, then sealed and allowed to react at 100° C. for 3 hours. After similar working up as in Example 45, 2.42 g (51.3%) of 2-ethoxy-7-hydroxy-2,4,4-trimethylchroman was obtained.

Provenance & Evidence