Ethanol → HCID 15124394, compound

HRID 1460827Notes

Reaction equation

HRID 1460827 reaction equation
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)O.[CH2:9]([O:11][C:12]([O:15][CH2:16][CH3:17])([CH3:14])[CH3:13])[CH3:10].[CH2:18](O)C.S(=O)(=O)(O)O>C1(C)C=CC=CC=1>[CH2:9]([O:11][C:12]1([CH3:14])[CH2:13][C:1]([CH3:3])([CH3:18])[C:8]2[C:16](=[CH:17][C:4]([OH:5])=[CH:6][CH:7]=2)[O:15]1)[CH3:10]

Participants

6

Reactant 4

HCID 702EthanolHCID 1118Sulfuric AcidHCID 5054ResorcinolHCID 31361Propane, 2,2-diethoxy-

Product 1

HCID 15124394HCID 15124394, compoundYield 51.3%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

100 ml stainless steel autoclave was charged with 2.2 g (20 mmol) of resorcin, 5.28 g (40 mmol) of acetone diethyl acetal, 9.2 g (200 mmol) of ethanol, 0.2 g (2 mmol) of conc. sulfuric acid and 40 ml of toluene, then sealed and allowed to react at 100° C. for 3 hours. After similar working up as in Example 45, 2.42 g (51.3%) of 2-ethoxy-7-hydroxy-2,4,4-trimethylchroman was obtained.

Workup

  1. customsealed
  2. customto react at 100° C. for 3 hours

Sources & evidence

ORD record
ord-14329f7fd38a44f1a01872fbcf7088b8
Source dataset
uspto-grants-1991_12
Patent number
US05072007

Reaction notes

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