Dichloromethane → HCID 19755541, compound

HRID 1460944Notes

Reaction equation

HRID 1460944 reaction equation
ClCCl.[N+:4]([C:7]1[CH:8]=[CH:9][C:10]([Cl:17])=[C:11]([S:13](Cl)(=[O:15])=[O:14])[CH:12]=1)([O-:6])=[O:5].[CH3:18][NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]>C(N(CC)CC)C>[CH3:18][N:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[S:13]([C:11]1[CH:12]=[C:7]([N+:4]([O-:6])=[O:5])[CH:8]=[CH:9][C:10]=1[Cl:17])(=[O:15])=[O:14]

Participants

5

Reactant 3

HCID 6344Dichloromethane2×HCID 206302-Chloro-5-nitrobenzenesulfonyl chlorideHCID 75539N-Methyloctadecylamine

Product 1

HCID 19755541HCID 19755541, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Dichloromethane (100 ml) was mixed with 44 grams of 5-nitro-2-chlorobenzenesulfonyl chloride and a dichloromethane solution which contained 48.4 grams of methyloctadecylamine and 36.1 ml of triethylamine was added dropwise to the mixture. After the reaction had been completed the reaction solvent was removed by distillation under reduced pressure, 300 ml of methanol was added and a solution was formed by heating. Crystals precipitated out on cooling the solution slowly and these were recovered by filtration and dried.

Workup

  1. additionwas added dropwise to the mixture
  2. customwas removed by distillation under reduced pressure, 300 ml of methanol
  3. additionwas added
  4. customa solution was formed
  5. temperatureby heating
  6. customCrystals precipitated out
  7. temperatureon cooling the solution slowly
  8. filtrationthese were recovered by filtration
  9. customdried

Sources & evidence

ORD record
ord-37cf9452f9f14022add47a1adf81974a
Source dataset
uspto-grants-1991_12
Patent number
US05073473

Reaction notes

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