Chloroform → Morpholine, 4-lauroyl-

HRID 1460950Notes

Reaction equation

HRID 1460950 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.C(=O)([O-])[O-].[K+].[K+].[C:13](Cl)(=[O:25])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24].C(Cl)(Cl)Cl>O>[O:25]=[C:13]([N:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

6

Reactant 4

HCID 6212ChloroformHCID 8083MorpholineHCID 8166Dodecanoyl chlorideHCID 11430Potassium Carbonate

Product 1

HCID 94793Morpholine, 4-lauroyl-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Example 1(A) was repeated using morpholine, potassium carbonate and dodecanoyl chloride in a biphasic mixture of chloroform and water followed by the usual workup to obtain the above product.

Workup

  1. customto obtain the above product

Sources & evidence

ORD record
ord-a4dc46b694df45868ba266f027a857b5
Source dataset
uspto-grants-1991_12
Patent number
US05073544

Reaction notes

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