Hydroxyamine hydrochloride → HCID 85546329, compound

HRID 1460962Notes

Reaction equation

HRID 1460962 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7](=O)[CH2:8][C:9]#[CH:10])[CH:2]=1.Cl.[NH2:13][OH:14]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7](=[N:13][OH:14])[CH2:8][C:9]#[CH:10])[CH:2]=1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 19981385HCID 19981385, compound

Product 1

HCID 85546329HCID 85546329, compound

Procedure

Employing the general method of Example 5 above, 2.95 g (18.5 mmol) of 1-(3-pyridinyl)-3-butyne-1-one was converted to 2.1 g (66%) of the corresponding oxime by reaction with hydroxylamine hydrochloride.

Sources & evidence

ORD record
ord-045fd0dfb2aa432cb172c491d600681b
Source dataset
uspto-grants-1991_12
Patent number
US05073561

Reaction notes

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