3-Pyridinecarboxaldehyde → HCID 131717102, compound

HRID 1460964Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[O:8])[CH:2]=1.[CH3:9][O:10][CH2:11][CH2:12][CH2:13]C1C=CN=CC=1CO>>[CH3:9][O:10][CH2:11][CH2:12][CH2:13][C:3]1([CH2:7][OH:8])[CH:4]=[CH:5][CH:6]=[N:1][CH2:2]1

Participants

Reactant 2

HCID 103713-Pyridinecarboxaldehyde

HCID 53995471HCID 53995471, compound

Product 1

HCID 131717102HCID 131717102, compound

Procedure

Following the general method of Example 1, 21.7 g (0.2 mol) of 4-chloro-1-methoxypropane and 21.4 g (0.2 mol) of pyridine-3-carboxaldehyde were converted to 18.87 g (52%) of (4-methoxypropyl-3-pyridinyl)methanol.

Sources & evidence

ORD record: ord-b465965f576d44cf9b2ff1c3c9390112
Source dataset: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05073561

Reaction notes

Loading…