HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-4'-hydroxybiphenyl → 4-[2-(4'-Fluoro-biphenyl-4-yloxy)-acetylamino]5-methyl-thiophene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-4'-hydroxybiphenyl | HCID 345420 | — |
| Reactant | 4-(2-Chloro-acetylamino)-5-methyl-thiophene-3-carboxylic acid methyl ester | HCID 68688343 | — |
| Product | 4-[2-(4'-Fluoro-biphenyl-4-yloxy)-acetylamino]5-methyl-thiophene-3-carboxylic acid | HCID 16068586 | — |
Reaction Steps
In analogy to Example 2, the title compound was prepared using 4-(2-chloro-acetylamino)-5-methyl-thiophene-3-carboxylic acid methyl ester [23964-99-0] and 4′-fluoro-biphenyl-4-ol. MS (m/e): 384.0 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732452B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-ed3734d12e754bea9c1f66535963ae46 |
| Source note | uspto-grants-2010_06 |