反应详情

A solution of 1-methylpiperazine (0.40 g, 4 mmole) in 5 ml benzene was added dropwise while stirring to a solution of (benzoyloxy)acetylchloride (0.80 g, 4 mmole) in 10 ml of benzene. After the addition was completed (about 10 min) the reaction mixture was stirred at room temperature for 1 h. Ether (10 ml) was added and the mixture was filtered. The white crystalline compound on the filter was washed with ether and finally recrystallized from ethanol, yielding 0.70 g (59%) of the title compound. Mp 227°-228° C.

1. additionAfter the addition
2. custom(about 10 min)
3. filtrationthe mixture was filtered
4. washThe white crystalline compound on the filter was washed with ether
5. customfinally recrystallized from ethanol