HCID 53958373, compound → HCID 19981501, compound

Participants

Reaction Steps

1.05 g of ethyl 6,6-diphenyl-8-dimethylaminonona-2,4-dienoate was dissolved in toluene (5 ml) and evaporated to dryness twice. The oil was taken up in 95% ethanol (25 ml) and placed in a Paar shaker bottle with 10% palladium on activated carbon (Pd/C, 190 mg). Paar shaker hydrogenation was conducted at room temperature and 60 psi pressure. After 1 hour, an additional 150 mg of catalyst were added and the hydrogenation reaction continued for 3 hours. TLC indicated complete reaction. The catalyst was removed by filtration, and the filtrate was concentrated to dryness to provide 863 mg of ethyl 6,6-diphenyl-8-dimethylaminononanoate, as a clear light yellow oil.

Provenance & Evidence