Hydrochloric Acid → HCID 10431897, compound

Participants

Reaction Steps

5-(4-[2-(N-Methyl-N-(2-benzoxazolyl)amino)ethylthio]-benzylidene)-2,4-thiazolidinedione (2 g) was dissolved in a mixture of methanol (70 ml) and 1,4-dioxan (70 ml). Magnesium turnings (1.7 g) were added and the solution stirred until no more effervescence was observed. The mixture was added to water (300 ml), acidified (2M HCl) to form a solution, neutralised (saturated NaHCO3 solution) and extracted with dichloromethane (3×150 ml). The organic extracts were washed with brine

Provenance & Evidence