HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyltin chloride → 2,6-Di(trifluoromethyl)-4-(trimethylstannyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyltin chloride | HCID 14016 | — |
| Reactant | 4-Bromo-2,6-bis(trifluoromethyl)pyridine | HCID 15030320 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2,6-Di(trifluoromethyl)-4-(trimethylstannyl)pyridine | HCID 15030321 | — |
Reaction Steps
2,6-Di(trifluoromethyl)-4-(trimethylstannyl)pyridine was prepared from 8.7 g 4-bromo-2,6-di(trifluoromethyl)pyridine, 12.4 ml butyllithium (24M in hexane) and 6 g trimethyltin chloride in 200 ml ether according to the procedure of Example 3, part (g), and was obtained (11 g) as a yellow semi-solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075319 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-0b987bf516d24f168c729342304deb79 |
| Source note | uspto-grants-1991_12 |