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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1461503Generated: October 27, 2026

7-demethylmitomycin A → Mitomycin A

https://huagongshe.com/reaction/1461503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-demethylmitomycin AHCID 11727393—
ReactantHCID 178486252HCID 178486252—
ProductMitomycin AHCID 19972—

Reaction Steps

7-Hydroxy-9a-methoxymitosane was alkylated with 3-methyl-I-p-tolyltriazene to give mitomycin A or with diazodiphenylmethane to give 7-(diphenylmethyl)oxy-9a-methoxymitosane (hereinafter 7-ODPM mitomycin).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05075454
Source datasetuspto-grants-1991_12
ORD IDord-682c5038d1b74fddbb288925f215c81d
Source noteuspto-grants-1991_12