Deferoxamine Mesylate → Zn Desferal

HRID 1461562Notes

Reaction equation

HRID 1461562 reaction equation
[CH3:1][C:2]([N:4]([OH:39])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([CH2:13][CH2:14][C:15]([N:17]([OH:38])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][NH:23][C:24]([CH2:26][CH2:27][C:28]([N:30]([OH:37])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][NH2:36])=[O:29])=[O:25])=[O:16])=[O:12])=[O:3].[CH3:40][S:41]([OH:44])(=[O:43])=[O:42].[Cl-].[Zn+2:46].[Cl-].O=C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>[Cl-].[Cl-].[Zn+2].O=C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>[Zn:46].[CH3:1][C:2]([N:4]([OH:39])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([CH2:13][CH2:14][C:15]([N:17]([OH:38])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][NH:23][C:24]([CH2:26][CH2:27][C:28]([N:30]([OH:37])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][NH2:36])=[O:29])=[O:25])=[O:16])=[O:12])=[O:3].[CH3:40][S:41]([OH:44])(=[O:43])=[O:42]

Participants

5

Reactant 3

HCID 62881Deferoxamine Mesylate2×HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 3007855Zincchloride

Product 1

HCID 86745316Zn Desferal

Reagents, catalysts & solvents 1

HCID 86745318ZnCl2 glucoseSolvent

Procedure

10 ml of sterile solution containing 500 mg Desferal, 10.4 mg zinc chloride and 1 gr of glucose is prepared by dissolving the contents of one vial of Desferal in ZnCl2 /glucose sterile solution.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-ffc009ac42aa404ea034372f3b2cf4c5
Source dataset
uspto-grants-1991_12
Patent number
US05075469

Reaction notes

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