HCID 54430555, compound → HCID 14998240, compound

HRID 1461677Notes

Reaction equation

HRID 1461677 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][CH2:10][CH2:11][O:12][N:13]2[C:17](=[O:18])[C:16]3=[CH:19][CH:20]=[CH:21][CH:22]=[C:15]3[C:14]2=[O:23])=[CH:4][CH:3]=1.[H][H]>O1CCCC1.[Pd]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][O:12][N:13]2[C:17](=[O:18])[C:16]3=[CH:19][CH:20]=[CH:21][CH:22]=[C:15]3[C:14]2=[O:23])=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 54430555HCID 54430555, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14998240HCID 14998240, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

71.5 g (0.23 mol) of N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide (prepared according to German Laid-Open Application DOS 3,838,310) were dissolved in 300 ml of tetrahydrofuran, 2 g of palladium on active carbon (10% strength) were added and hydrogenation was carried out under slightly superatmospheric pressure until 1.2 times the theoretical amount of hydrogen had been consumed.

Workup

  1. customhad been consumed

Sources & evidence

ORD record
ord-69a9cb9357e441fdb5e8944a4cdde44b
Source dataset
uspto-grants-1991_12
Patent number
US05076831

Reaction notes

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