4-(Dimethylamino)butyronitrile → HCID 14882752, compound

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Reaction Steps

The amine of formula III, when n is equal to 3, p equal to 2 and q equal to zero, is prepared from 4-(N,N-dimethylamino)butyronitrile. This compound is condensed with 3-chloro-l-iodopropane to form 2-[2-(N,N-dimethylamino) ethyl]-5-chloropentanenitrile which, after cyclization, gives 4-cyano-l-methylperhydroazepine. From this compound and using conventional methods, the expected amine is obtained.

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