反应详情

The compound obtained in Stage F, 9.7 g of 3-(2-chloroethyl)-8-cyano-4-hydroxy-2-methylimidazo[1,5-a]-pyrimidine, 23 g of sodium carbonate, 0.5 g of potassium iodide and 800 ml of 4-methyl-2-pentanone are brought to reflux. The procedure then adopted is as described in Example 1, Stage C, to obtain the expected hydrochloride.

1. temperatureto reflux