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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1461792Generated: November 1, 2026

Methyl 4-(4-oxocyclohexyl)benzoate → 2-Carbomethoxy-4-(4'-carbomethoxyphenyl)cyclohexanone

https://huagongshe.com/reaction/1461792

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(4-oxocyclohexyl)benzoateHCID 15023908—
Reactantdimethylcarbonate NaHHCID 86745363—
SolventTetrahydrofuranHCID 8028—
Product2-Carbomethoxy-4-(4'-carbomethoxyphenyl)cyclohexanoneHCID 1571920063%

Reaction Steps

Compound 14 was acylated with dimethylcarbonate/NaH/-KH in THF to give 15 (63%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05077404
Source datasetuspto-grants-1991_12
ORD IDord-26520cd213d4445daa2dd0612026a836
Source noteuspto-grants-1991_12