反应详情

A mixture of 3.6 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 3.46 g of 5-methylthiazole in 25 ml of toluene is refluxed under inert gas for 1.5 hours, cooled and poured into 200 ml of ether. The organic layer is decanted and the solid washed with ether and collected to give 3.8 g of the desired product as a white solid, m.p. 173°-175° C.

1. temperatureis refluxed under inert gas for 1.5 hours
2. temperaturecooled
3. customThe organic layer is decanted
4. washthe solid washed with ether
5. customcollected