HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 10008954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 5-Methylthiazole | HCID 137980 | — |
| Reactant | N-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamide | HCID 10052253 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 10008954 | HCID 10008954 | 88.6% |
Reaction Steps
A mixture of 3.6 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 3.46 g of 5-methylthiazole in 25 ml of toluene is refluxed under inert gas for 1.5 hours, cooled and poured into 200 ml of ether. The organic layer is decanted and the solid washed with ether and collected to give 3.8 g of the desired product as a white solid, m.p. 173°-175° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05077409 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-b6580ac40f8c46c1b7c02ee88b27d5c9 |
| Source note | uspto-grants-1991_12 |