HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Cyclohexaneacetic acid, 3,3,5-trimethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl (3,3,5-trimethylcyclohexyl)acetate | HCID 122545 | — |
| Solvent | Water | HCID 962 | — |
| Product | Cyclohexaneacetic acid, 3,3,5-trimethyl- | HCID 102954 | 83% |
Reaction Steps
875 g of ethyl 3,3,5-trimethyl-cyclohexylacetate are treated in 2.2 l of water with 670 g of 30% sodium hydroxide and the mixture is held at reflux temperature for 21/2 hours while stirring. After cooling, the mixture is neutralized, acidified with 420 g of 63% sulphuric acid and extracted with cyclohexane. The cyclohexane extract is washed neutral, evaporated and the 770 g of crude product are distilled. There are obtained 630 g of 3,3,5-trimethyl-cyclohexylacetic acid. (Yield: 82%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04457862 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-7d55fbf5e5534c99b9480ca9485b6e28 |
| Source note | uspto-grants-1984_07 |