HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-(3,5-Dimethylcyclohexyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 3,5-dimethyl-cyclohexylacetate | HCID 20454256 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(3,5-Dimethylcyclohexyl)acetic acid | HCID 20454253 | 92.8% |
Reaction Steps
44.7 g of ethyl 3,5-dimethyl-cyclohexylacetate are treated with 300 ml of methanol and 15 g of potassium hydroxide, dissolved in 140 ml of water, and saponified by heating to reflux temperature for 3 hours. The working-up yields 35.6 g of a solid crude product which is used directly. A sample is distilled for the purpose of analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04457862 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-0e1b52d2bf2e46028835f48ad4fda108 |
| Source note | uspto-grants-1984_07 |