1-Methylpiperazine → HCID 13324579, compound

Participants

Reaction Steps

To a mixture of 1.2 g of N-methylpiperazine and 20 ml of methanol was added gradually 2 g of ethyl 5-cyano-2-hydroxyoxanilate and after stirring the mixture for 3 hours at room temperature, crystals formed were recovered by filtration, washed successively with isoporpnaol and ether, and dried to provide 2 g of 1-(5-cyano-2-hydroxyoxanilyl)-4-methylpiperazine.

Provenance & Evidence