Dichromate ion → HCID 70466070, compound

HRID 1461992Notes

Reaction equation

HRID 1461992 reaction equation
[Cl:1][C:2]1[C:3]2([O:25][CH2:24][CH2:23][O:22]2)[CH2:4][C@H:5]2[C@:18]([CH3:20])([CH:19]=1)[C@@H:17]1[C@H:8]([C@H:9]3[C@@:13]([CH2:15][CH2:16]1)([CH3:14])[C@@H:12]([OH:21])[CH2:11][CH2:10]3)[CH2:7][CH2:6]2.[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O>CN(C)C=O>[Cl:1][C:2]1[C:3]2([O:22][CH2:23][CH2:24][O:25]2)[CH2:4][C@H:5]2[C@:18]([CH3:20])([CH:19]=1)[C@@H:17]1[C@H:8]([C@H:9]3[C@@:13]([CH2:15][CH2:16]1)([CH3:14])[C:12](=[O:21])[CH2:11][CH2:10]3)[CH2:7][CH2:6]2

Participants

4

Reactant 2

HCID 24503Dichromate ionHCID 70466692HCID 70466692, compound

Product 1

HCID 70466070HCID 70466070, compoundYield 100.6%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

5.0 g of 2-chloro-3,3-ethylenedioxy-5α-androst-1-en-17β-ol is stirred in 50 ml of dimethylformamide with 10 g of pyidinium dichromate for 17 hours at room temperature and then worked up as described in Example 10B. After evaporation, 5 g of 2-chloro-3,3-ethylenedioxy-5α-androst-1-en-17-one is obtained.

Workup

  1. customAfter evaporation

Sources & evidence

ORD record
ord-ef04368b0c1e47628795403884d3df1d
Source dataset
uspto-grants-1984_07
Patent number
US04457925

Reaction notes

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