反应详情

4-Cyano-5-diacetylamino-1-(2,3,4-trichlorophenyl)pyrazole (0.2 g) in ethanol (5 ml) containing saturated aqueous sodium bicarbonate solution (4 drops), was heated at reflux for 20 minutes. The reaction mixture was then evaporated to dryness under reduced pressure (20 mmHg) to give a fawn coloured powder which was crystallized from ethanol (2 ml), to give 5-acetamido-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole (0.09 g), m.p. 222°-224° C., in the form of a colourless crystalline solid.

1. temperaturewas heated
2. temperatureat reflux for 20 minutes
3. customThe reaction mixture was then evaporated to dryness under reduced pressure (20 mmHg)
4. customto give a fawn
5. customwas crystallized from ethanol (2 ml)