反应详情

5-Amino-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole (2.9 g) in acetylchloride (15 mg) was heated at reflux for 2 hours. The reaction mixture was then filtered and the solid residue was triturated with acetyl chloride (10 ml), to give 5-acetamido-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole (2.0 g), m.p. 220°-223° C., in the form of a colourless powder.

1. temperatureat reflux for 2 hours
2. filtrationThe reaction mixture was then filtered
3. customthe solid residue was triturated with acetyl chloride (10 ml)