HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 5-Acetamido-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 5-amino-1-(2,3,4-trichlorophenyl)-1H-pyrazole-4-carbonitrile | HCID 3018901 | — |
| Product | 5-Acetamido-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole | HCID 13127529 | 3,175.8% |
Reaction Steps
5-Amino-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole (2.9 g) in acetylchloride (15 mg) was heated at reflux for 2 hours. The reaction mixture was then filtered and the solid residue was triturated with acetyl chloride (10 ml), to give 5-acetamido-4-cyano-1-(2,3,4-trichlorophenyl)pyrazole (2.0 g), m.p. 220°-223° C., in the form of a colourless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04459150 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-787dc3162a6741abb74640f237d117a1 |
| Source note | uspto-grants-1984_07 |