Hydrogen Bromide → HCID 131713576, compound

HRID 1462154Notes

Reaction equation

HRID 1462154 reaction equation
C(OC([NH:11][CH2:12][C:13]([NH:15][C:16]([C:24]([N:26]1[CH2:33][CH2:32][CH2:31][C@H:27]1[C:28]([NH2:30])=[O:29])=[O:25])=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:14])=O)C1C=CC=CC=1.[BrH:34]>C(O)(=O)C>[BrH:34].[NH2:11][CH2:12][C:13]([NH:15][C:16]([C:24]([N:26]1[CH2:33][CH2:32][CH2:31][C@H:27]1[C:28]([NH2:30])=[O:29])=[O:25])=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:14]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 131713578HCID 131713578, compound

Product 1

HCID 131713576HCID 131713576, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1.3 g of benzyloxycarbonyl-glycyl-dehydrophenylalanyl-prolinamide are dissolved in 6 ml of 30% HBr in glacial acetic acid. After a reaction time of 20 minutes, at room temperature, the product is precipitated with ether, centrifuged and washed several times with ether.

Workup

  1. customAfter a reaction time of 20 minutes, at room temperature, the product is precipitated with ether
  2. washcentrifuged and washed several times with ether

Sources & evidence

ORD record
ord-b7172e3f8bd24a10b6dd072fc92ef8ef
Source dataset
uspto-grants-1984_07
Patent number
US04459225

Reaction notes

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