Hydantoin → HCID 20454111, compound

HRID 1462201Notes

Reaction equation

HRID 1462201 reaction equation
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[NH:9]1[CH2:15][C:13](=[O:14])[NH:12][C:10]1=[O:11]>O1CCOCC1>[O:8]=[C:3]1[N:4]=[C:5]([N:9]2[CH2:15][C:13](=[O:14])[NH:12][C:10]2=[O:11])[CH2:6][O:1][NH:2]1

Participants

4

Reactant 2

HCID 10006HydantoinHCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-

Product 1

HCID 20454111HCID 20454111, compoundYield 41%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of 1.0 g (0.0075 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione in 50 ml of freshly distilled dry dioxane is added 0.77 g (0.0077 mole) of hydantoin. After stirring at room temperature for 17 hours, the solution is filtered, washed with chloroform and dried to give a yield of 0.6 g (41 percent) of 1-(3,6-dihydro-3-oxo-2H-1,2,4-oxadiazin-5-yl)-2,4-imidazolidinedione.

Workup

  1. filtrationthe solution is filtered
  2. washwashed with chloroform
  3. customdried

Sources & evidence

ORD record
ord-98a0acb4a4e34e86a6817b12f43a520e
Source dataset
uspto-grants-1984_07
Patent number
US04459403

Reaction notes

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