Piperidine → HCID 20454107, compound

HRID 1462204Notes

Reaction equation

HRID 1462204 reaction equation
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[NH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>O1CCOCC1>[N:9]1([C:5]2[CH2:6][O:1][NH:2][C:3](=[O:8])[N:4]=2)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

4

Reactant 2

HCID 8082PiperidineHCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-

Product 1

HCID 20454107HCID 20454107, compoundYield 54%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of 0.7 g (0.005 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione in 10 ml of dry freshly distilled dioxane is added 0.44 g (0.0052 mole) of piperidine. After stirring for 17 hours at room temperature, the solution is filtered, washed with chloroform and dried to give a yield of 0.49 g (54 percent) of 5-(1-piperidinyl)-6H-1,2,4-oxadiazin-3(2H)-one.

Workup

  1. filtrationthe solution is filtered
  2. washwashed with chloroform
  3. customdried

Sources & evidence

ORD record
ord-e0888ee7576f44258efc6420c42c0acc
Source dataset
uspto-grants-1984_07
Patent number
US04459403

Reaction notes

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