Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1462407Generated: October 31, 2026

Isopropanol → Isopropyl 2-[2-phenyl-5-(3-thienyl)-4-oxazolyl]acetate

https://huagongshe.com/reaction/1462407

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropanolHCID 3776—
ReactantThionyl ChlorideHCID 24386—
Reactant2-[2-Phenyl-5-(3-thienyl)-4-oxazolyl]acetic acidHCID 13105439—
ProductIsopropyl 2-[2-phenyl-5-(3-thienyl)-4-oxazolyl]acetateHCID 1310544443%

Reaction Steps

2 g of 2-[2-phenyl-5-(3-thienyl)-4-oxazolyl]acetic acid, 3 g of thionyl chloride and 30 ml of isopropanol are treated in the same manner as described in Example 13. One g of isopropyl 2-[2-phenyl-5-(3-thienyl)-4-oxazolyl]acetate is obtained. Yield: 43%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04460596
Source datasetuspto-grants-1984_07
ORD IDord-49243c4e141c4cddb9903f36fb1294a8
Source noteuspto-grants-1984_07