Methane → HCID 178430864, compound

Participants

Reaction Steps

A mixture of 16 g of 2-methyl-11H-imidazo[1,2-c][1,3]bezodiazepine-5-(6H)-one, 9.58 g of N-methylpiperazine and 160 ml of methylene chloride is stirred at room temperature overnight. The mixture is decolorized with charcoal and evaporated to dryness. The residue is crystallized from methanol-ether to give 1-[2-(4-methyl-2-imidazolylmethyl) phenylcarbamoyl]-4-methylpiperazine, m.p. 177°-179°.

Provenance & Evidence