Phosphorus pentachloride → Ethoxy(6-phthalimidohexyl)phosphinyl chloride

HRID 1462488Notes

Reaction equation

HRID 1462488 reaction equation
[C:1]1(=[O:25])[N:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][P:12](=O)([O:16]CC)[O:13][CH2:14][CH3:15])[C:4](=[O:20])[C:3]2=[CH:21][CH:22]=[CH:23][CH:24]=[C:2]12.P(Cl)(Cl)(Cl)(Cl)[Cl:27]>C1C=CC=CC=1>[Cl:27][P:12]([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:4](=[O:20])[C:3]2=[CH:21][CH:22]=[CH:23][CH:24]=[C:2]2[C:1]1=[O:25])(=[O:16])[O:13][CH2:14][CH3:15]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 2565802-(6-diethoxyphosphorylhexyl)isoindole-1,3-dione

Product 1

HCID 256577Ethoxy(6-phthalimidohexyl)phosphinyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of (6-phthalimidohexyl)phosphonic acid, diethyl ester, benzene, and phosphorus pentachloride is refluxed according to the procedure of Example 1(e) to give chloro(6-phthalimidohexyl) phosphinic acid, ethyl ester.

Workup

  1. temperatureis refluxed

Sources & evidence

ORD record
ord-4e1f5296c47040579c022e6103d53556
Source dataset
uspto-grants-1984_07
Patent number
US04460579

Reaction notes

Loading…