Dichloromethane → 5'-Amino-2'-trifluoromethoxy-biphenyl-4-carboxylic acid {4-[4-(propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenyl}-amide
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][c:10](-[c:19]2[cH:20][cH:21][c:22]([C:25]([NH:26][c:27]3[cH:28][cH:29][c:30]([CH2:33][N:34]4[CH2:35][CH2:36][N:37]([S:40](=[O:41])(=[O:42])[CH2:43][CH2:44][CH3:45])[CH2:38][CH2:39]4)[cH:31][cH:32]3)=[O:46])[cH:23][cH:24]2)[c:11]([O:14][C:15]([F:16])([F:17])[F:18])[cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:47].[Cl:48][CH2:49][Cl:50].[OH:51][C:52]([C:53]([F:54])([F:55])[F:56])=[O:57]>>[NH2:7][c:8]1[cH:9][c:10](-[c:19]2[cH:20][cH:21][c:22]([C:25]([NH:26][c:27]3[cH:28][cH:29][c:30]([CH2:33][N:34]4[CH2:35][CH2:36][N:37]([S:40](=[O:41])(=[O:42])[CH2:43][CH2:44][CH3:45])[CH2:38][CH2:39]4)[cH:31][cH:32]3)=[O:46])[cH:23][cH:24]2)[c:11]([O:14][C:15]([F:16])([F:17])[F:18])[cH:12][cH:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ec8af7cff90e4b3f8a8f15d9b97d29ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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