Sodium Iodide → HCID 178469086, compound

Participants

Reaction Conditions

Reaction Steps

2.2 g of 1-acetylimidazole, 5.5 g of ethyl 4-(2-bromoethoxy)benzoate, and 3.0 g of sodium iodide were added to 10 ml of dry acetonitrile, and the mixture was heated in a sealed tube under nitrogen atmosphere at 100° C. for 6 hours. After the reaction mixture was cooled, the insoluble materials were filtered off and the filtrate was concentrated under reduced pressure. The residue was triturated with an adequate amount of dry diethyl ether and the r resulting powder was collected by filtration and dried to obtain 6.2 g of 1-acetyl-3-[2-(4-ethoxycarbonylphenoxy)-ethyl]imidazolium iodide (72% yield). Colorless hygroscopic amorphous.

Provenance & Evidence