反应详情

温度

100 °C

2.2 g of 1-acetylimidazole, 5.5 g of ethyl 4-(2-bromoethoxy)benzoate, and 3.0 g of sodium iodide were added to 10 ml of dry acetonitrile, and the mixture was heated in a sealed tube under nitrogen atmosphere at 100° C. for 6 hours. After the reaction mixture was cooled, the insoluble materials were filtered off and the filtrate was concentrated under reduced pressure. The residue was triturated with an adequate amount of dry diethyl ether and the r resulting powder was collected by filtration and dried to obtain 6.2 g of 1-acetyl-3-[2-(4-ethoxycarbonylphenoxy)-ethyl]imidazolium iodide (72% yield). Colorless hygroscopic amorphous.

1. temperatureAfter the reaction mixture was cooled
2. filtrationthe insoluble materials were filtered off
3. concentrationthe filtrate was concentrated under reduced pressure
4. customThe residue was triturated with an adequate amount of dry diethyl ether
5. customthe r resulting powder
6. filtrationwas collected by filtration
7. customdried