Methyl iodide → HCID 13191642, compound

Participants

Reaction Steps

12.0 g (0.047 mole) of ethyl 1,2,4-triazolo[1,5-c]quinazolin-5-one-2-carboxylate in 100 ml of absolute dimethylformamide were added dropwise to a suspension of 0.053 mole of NaH in 100 ml of absolute dimethylformamide at room temperature. After 2 hours, 7.5 g (0.053 mole) of methyl iodide were added, and the mixture was stirred overnight at room temperature and then poured into 400 ml of ice water. The precipitate was filtered off under suction and dried. Yield: 6.6 g (52%), mp.: 258° C.

Provenance & Evidence