HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178448682, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl cyanoacetate | HCID 7747 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Sec-Butylamine | HCID 24874 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178448682 | HCID 178448682 | — |
Reaction Steps
A mixture composed of 130 g (1 mol) of ethyl acetoacetate, 99 g (1 mol) of methyl cyanoacetate, 146 g (2 mol) of sec-butylamine and 300 ml of methanol was heated in an autoclave at 100° to 110° C. for 10 hours. After cooling, the reaction solution was neutralized with diluted hydrochloride to obtain white crystals of 1-sec-butyl-3-cyano-6-hydroxy-4-methyl-2-pyridone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04463079 |
| Source dataset | uspto-grants-1984_07 |
| ORD ID | ord-c1289dd1aca34003af68f01de4c103c8 |
| Source note | uspto-grants-1984_07 |