(4-Amino-3-nitrophenyl)acetonitrile → HCID 14891906, compound

HRID 1463160Notes

Reaction equation

HRID 1463160 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]#[N:10])=[CH:4][C:3]=1[N+:11]([O-])=O>C(O)C.[Pd]>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]#[N:10])=[CH:4][C:3]=1[NH2:11]

Participants

4

Reactant 1

HCID 14891905(4-Amino-3-nitrophenyl)acetonitrile

Product 1

HCID 14891906HCID 14891906, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 1-amino-2-nitro-4-cyanomethylbenzene (6 g.) in ethanol (100 ml.) was hydrogenated for 1.5 hour at atmospheric pressure in presence of 3.6 g. of 10% w/w Pd/C. The catalyst was removed and the solvent was evaporated to give 1,2-diamino-4-cyanomethylbenzene which was used without further purification.

Workup

  1. customThe catalyst was removed
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-7c81f0484f1f4f928e631eec9aaac12e
Source dataset
uspto-grants-1984_07
Patent number
US04463173

Reaction notes

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