HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetohydrazide → 2-Fluoro-6-(4-methyl-1-piperazinyl)pyridine-3-carboxaldehyde acetylhydrazone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetohydrazide | HCID 14039 | — |
| Reactant | 2-Fluoro-6-(4-methyl-1-piperazinyl)pyridine-3-carboxaldehyde | HCID 10632859 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Fluoro-6-(4-methyl-1-piperazinyl)pyridine-3-carboxaldehyde acetylhydrazone | HCID 54113310 | — |
Reaction Steps
2-Fluoro-6-(4-methyl-1-piperazinyl)pyridine-3-carboxaldehyde (3.35 g, 0.015 mole) was dissolved in 20 mL of EtOH and treated with acetylhydrazine (2.2 g, 0.030 mole). This reaction mixture was stirred for 72 hours and then the product was filtered off and recrystallized from EtOAc to give 2.85 g, mp 210°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05300498 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-3d9466cf7d4e46898deb660729bc7032 |
| Source note | uspto-grants-1994_04 |