Triethylamine → 4,6-Diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenylmethoxy)-1,3,5-triazine

HRID 1463288Notes

Reaction equation

HRID 1463288 reaction equation
Br.[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[N:6]([O:10][CH2:11][C:12]2[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:13]=2[Cl:20])[C:5]([CH3:22])([CH3:21])[N:4]=1.C(N(CC)CC)C>O>[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[N:6]([O:10][CH2:11][C:12]2[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:13]=2[Cl:20])[C:5]([CH3:22])([CH3:21])[N:4]=1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 190899624,6-Diamino-1,2-dihydro-1-(2,4,5-trichlorophenylmethoxy)-2,2-dimethyl-1,3,5-triazine hydrobromide

Product 1

HCID 190899634,6-Diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenylmethoxy)-1,3,5-triazineYield 114.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 0.5 gram (0.001 mole) of 4,6-diamino-1,2-dihydro 2,2-dimethyl-1-(2,4,5-trichlorophenylmethoxy)-1,3,5-triazine hydrobromide (Compound 60 - Prepared in Example 3) in 30 ml of water was stirred and 1 ml (0.007 mole) of triethylamine was added. The resultant solid was collected by filtration and dried, yielding 0.4 gram of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenylmethoxy)-1,3,5-triazine. The NMR spectrum was consistent with the proposed structure.

Workup

  1. filtrationThe resultant solid was collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-dfeb086d755f430e97c46bf817821bfe
Source dataset
uspto-grants-1994_04
Patent number
US05300503

Reaction notes

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