Hydrochloric Acid → HCID 19090056, compound

HRID 1463305Notes

Reaction equation

HRID 1463305 reaction equation
[C:1]([O:10][CH3:11])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[CH2:12]1[C:17](=[O:18])[O:16][CH2:15][C:13]1=O.Cl>C(O)C>[O:18]=[C:17]1[O:16][CH:15]([NH:4][C:3]2[C:2](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:1]([O:10][CH3:11])=[O:9])[CH:13]=[CH:12]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8635Methyl AnthranilateHCID 521261Tetronic acid

Product 1

HCID 19090056HCID 19090056, compoundYield 91.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

15.1 gm of methyl anthranilate and 9.0 gm of β-tetronic acid were dissolved into 100 ml of ethanol, and 2 ml of concentrated hydrochloric acid was added, followed by stirring for 15 hours at room temperature. Deposited crystals were collected by filtration, washed with cold ethanol, and dried to obtain 19.2 gm of methyl N-(2,5-dihydro-5-oxo-2-furanyl)anthranilate.

Workup

  1. additionwas added
  2. filtrationDeposited crystals were collected by filtration
  3. washwashed with cold ethanol
  4. customdried

Sources & evidence

ORD record
ord-98b91115efa743f2bc4f497333c4799f
Source dataset
uspto-grants-1994_04
Patent number
US05300517

Reaction notes

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