HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19090869, compound → HCID 19090866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19090869 | HCID 19090869 | — |
| Reactant | HCID 178476777 | HCID 178476777 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 19090866 | HCID 19090866 | — |
Reaction Steps
A solution of 1.46 g of 3-(N-tert.-butyloxycarbonylamino)-2-(4-chlorophenyl)-propionaldehyde, 0.54 g of ethyl methylphosphinate and 0.695 ml of triethylamine is heated to 100° for 2 hours. The reaction mixture is cooled to room temperature and chromatographed on silica gel to give ethyl 3-(N-tert.-butyloxycarbonylamino)-2-(4-chlorophenyl)-1-hydroxypropyl(methyl)phosphinate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05300679 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-32aaa26307d84181bf35ccec89c9feba |
| Source note | uspto-grants-1994_04 |