Dichloromethane → HCID 67749684, compound

Participants

Reaction Steps

A 1 g (0.018 mole) quantity of calcium oxide was suspended in 100 mL of distilled water, and 4 g (0.013 mole) of 4-hexyl-3-hydroxy-2,2-dimethyl-5-phenyl-4-pentenoic acid was added to the suspension. After stirring for 4 days at room temperature, 50 mL of dichloromethane was added to the suspension and the mixture was stirred vigorously for 30 minutes. Another 50 mL of dichloromethane was added and the aqueous layer was separated. The aqueous phase was washed with 50 mL of dichloromethane, and the combined organic phase was evaporated to dryness to provide 4.8 g of crude product.

Provenance & Evidence