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HRID14638

反应详情

EQUATION

反应方程式

HRID 14638 的结构方程式

REACTANTS

反应物

2
结构：CNCCc1ccccn1
HCID2366

Betahistine

C8H12N2

结构：COc1cc(OC)c2c(CNC(=O)OC(C)(C)C)ncc(C(=O)O)c2c1
HCID59341098

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(OC)c2c(CNC(=O)OC(C)(C)C)ncc(C(=O)N(C)CCc3ccccn3)c2c1
HCID68613832

未命名化合物

PROCEDURE

实验过程

As described in example 1E, 100 mg of 1-(tert-butoxycarbonylamino-methyl)-6,8-dimethoxy-isoquinoline-4-carboxylic acid was coupled with methyl-(2-pyridin-2-yl-ethyl)-amine to give 66 mg of {6,8-dimethoxy-4-[methyl-(2-pyridin-2-yl-ethyl)-carbamoyl]-isoquinolin-1-ylmethyl}-carbamic acid tert-butyl ester. MS: APCI (M+H) calc'd for C26H32N4O5+H 481.6; found 481.0.